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Information about Polyneuropathy

Polyneuropathy

Polyneuropathies are a group of diseases that affect multiple nerves in any combination. They may be inherited or acquired later in life.

Inherited Causes

  • Spinal muscular atrophy, which is shrinkage of the muscles of the spine 
  • Demyelination, which is destruction of the covering of the nerves 
  • Lysosomal storage diseases are inherited deficiencies of particular enzymes creating an inability to perform normal metabolic functions

Acquired Causes

 

  • Immune-mediated or associated with a hyperactive immune system
  • Systemic lupus erythematosus, which is a multi-organ immune disease
  • Polymyositis, or inflammation of the muscles
  • Polyarthritis, or inflammation of the joints
  • Glomerulonephritis, or inflammation of a part of the kidneys

Infectious Causes

 

  • Neospora canis, a protozoa

Metabolic Causes

  • Diabetes mellitus
  • Hypothyroidism
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